A considerable amount of research into palm crease and fingerprint whorl variations has been undertaken in mainstream scientific journals, generally with respect to the usefulness of these phenotypic markers in diagnosing genetic medical disorders. Such research has uncovered strong correlations between both the single palmar crease and aberrant fingerprints and chromosomal disorders such as cri du chat syndrome (chromosome), aberrations on chromosome, Noonan syndrome (chromosome), Patau syndrome (chromosome), Edward's syndrome (chromosome 18), Down syndrome (chromosome), and Aarskog-Scott syndrome.
Aberrent digit length, which can include having one or more unusually short fingers (brachydactyly) or severely incurved fingers (clinodactyly). has also been scientifically correlated with numerous genetic chromosomal disorders and congenital syndromes.
John T. Manning has linked digit ratios to other conditions, such as prenatal androgen exposure, sexual dimorphism, homosexuality, depression, reproductive success, and musical aptitude.
There has been little widely accepted research verifying palmistry's accuracy as a system of character analysis, and so far no conclusive evidence has been provided to support a connection between the lines of the palm and a person's character beyond what could be deduced from analyzing that the person suffered from a chomosomal disorder or belonged to a certain statistical group based on their digit ratio. No conclusive data have yet been found to support the claims made by hand readers with respect to life expectancy or personality type.
Skeptics often include palmists on lists of alleged psychics who practice a technique called cold reading. Cold reading is cited as the practice that allows readers of all kinds, including palmists, to appear psychic. Although fortune telling is much less common today in mainstream palmistry than it was in the past, sceptics almost always associate palmistry with fortune telling rather than reading character.
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